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Treating Nonmetastatic Breast Cancer in 2019

29:05 | May 7th

Breast cancer outcomes continue to improve. Treatments for the disease are very effective and continually evolving. We spoke with Patricia A. Ganz, MD, from UCLA about what is new in breast cancer treatment. Read the article here.
JAMA Women's Health Series Introduction by Dr Carolyn Crandall

02:58 | May 7th

Dr Carolyn Crandall, professor of medicine at the David Geffen School of Medicine at UCLA and JAMA Associate Editor, introduces JAMA's new series of articles on women's health.
Beyond the Rhetoric: Gun Control That Works, Part 3

25:17 | Apr 9th

Congressman Mike Thompson chairs the US House Gun Violence Prevention Taskforce. He spoke with us about what the House has done to address gun violence and what you can do to help them see necessary legislation make it into law. We also talk with Jos...Show More
How to Reduce Maternal Mortality Rates in the United States

27:38 | Apr 2nd

Maternal mortality rates in most of the United States are high. These rates were successfully lowered in the United Kingdom and also in California. Many of these deaths are preventable. In this podcast we interview Elizabeth A. Howell, MD, MPP, from ...Show More
Beyond the Rhetoric: Gun Control That Works, Part 2

26:04 | Mar 26th

Almost nothing is more controversial than gun control in the United States. Yet while passions flare and legislators posture but do little, deaths from gun violence are all too common. Almost every proposal put forward to address gun violence eventua...Show More
Update on Atrial Fibrillation: Review of the New AHA/ACC/HRS Treatment Guidelines

42:01 | Mar 15th

Cardiologist and JAMA Deputy Editor Greg Curfman, MD, discusses the many changes in the new AHA/ACC/HRS atrial fibrillation guidelines with University of Chicago cardiologists Gaurav Upadhyay, MD, and Francis Alenghat, MD, PhD. Major changes include ...Show More
Beyond the Rhetoric: Gun Control That Works, Part 1

27:45 | Mar 12th

Almost nothing is more controversial than gun control in the United States. Yet while passions flare and legislators posture but do little, deaths from gun violence are all too common. Almost every proposal put forward to address gun violence eventua...Show More
Is It Safe? What Happens When Your Surgeon Is Not Actually Doing Some of Your Operation?

24:43 | Feb 26th

Great controversy exists regarding the safety of surgery when the attending surgeon allows someone else to perform parts of the operation. These practices are necessary components of surgical training, but how safe this is for patients remains unknow...Show More
COPD: All You Need to Know in 20 Minutes

21:52 | Feb 26th

COPD is common enough that it is responsible for 3% of all clinic visits in the United States. Clinicians will undoubtedly deal with this disease in their practice. How to diagnose and manage it is reviewed by Frank C. Sciurba, MD, a professor of med...Show More
Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice

25:11 | Feb 14th

Next-generation sequencing is a catchall term for new, high-throughput technologies that allow rapid sequencing of a full genome. It can be used to sequence a patient’s DNA in diagnosing a genetic disorder or characterizing a cancer, but can also be ...Show More
Can I Believe the Results From Observational Studies? Using E-Values That Anyone Can Calculate for Evaluating the Risk of Confounding

28:14 | Feb 12th

E-values are a new tool that enables investigators to estimate the likelihood that some unmeasured confounder might overcome seemingly positive results. They are very easy to calculate and any reader of the medical literature can do this calculation ...Show More
Your Watch Can Tell You the Time and If You Are About to Die From a Cardiac Arrhythmia

14:53 | Jan 29th

Saved by a Fitbit. Technology is developing at a pace far exceeding its application in medical care. An exception is in consumer devices, which as long as they do not hold themselves out as diagnostic tools, can apply as many technologies to wearable...Show More
Screening for Breast Cancer: Is It Worth It?

17:55 | Jan 22nd

Breast cancer screening is debated passionately among those who advocate for very aggressive screening and other experts who believe that screening can be harmful. The arguments for all sides of the debate are best understood by knowing the numbers o...Show More
Major Societies Agree – A New Approach to Penicillin Allergy Is Needed

35:35 | Jan 15th

Very few people who think they are allergic to penicillin actually are. Yet, even if someone reports a remote and vague history of penicillin allergy, these very useful medications will not be given. This forces many patients to use antibiotics that ...Show More
Medical Emergencies While Flying

29:22 | Dec 21st, 2018

When flying and they call "Is there a licensed medical professional on board," should physicians respond? If so, what should they do? Are they liable if things go wrong? We interview Christian Martin-Gill, MD, MPH, Department of Emergency Medicine, U...Show More
Bayes for Clinicians Who Need to Know but Don’t Like Math

28:32 | Dec 11th, 2018

The statistical concept of Bayes comes up in clinical medicine all the time. It simply means that what you know about something factors into how you analyze it. This contrasts with the commonly used statistical approach called frequentist analysis of...Show More
Battle of the Heart Societies, Part 2: Who Is Right – the US or Europe Regarding How to Manage Hypertension? Their Differences

38:27 | Nov 20th, 2018

Within the last 2 years, major guidelines have been issued from US-based and European organizations that differ in their recommendations for the diagnosis and treatment of hypertension. Experts from both sides of the Atlantic--Paul Whelton, MD, from ...Show More
A Family’s Struggle With Alcoholism

31:21 | Nov 13th, 2018

What is it like to go through alcohol withdrawal at home? What is it like for a mother to sit by her son's side while he goes through withdrawal and supporting him? Why does someone who doesn't have any particular reason to drink misuse alcohol? The ...Show More
Battle of the Heart Societies: Who Is Right – the US or Europe Regarding How to Manage Hypertension?

32:25 | Nov 6th, 2018

Within the last 2 years, major guidelines have been issued from US-based and European organizations that differ in their recommendations for the diagnosis and treatment of hypertension. Experts from both sides of the Atlantic—Paul Whelton, MD, from t...Show More
Observations From ICU Patients We Thought Were Asleep, but Were Not

25:44 | Oct 23rd, 2018

What if the patient you are managing in the ICU is not asleep when you thought they were? Patients relate their very disturbing stories about what they experienced while in an ICU and their treating clinicians thought they were asleep.
An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease

17:19 | Oct 16th, 2018

Venous thromboembolic disease is common. There are many steps necessary to establish a diagnosis or treat this disease. These are summarized in this JAMA Clinical Reviews podcast and interview with Philip S. Wells, MD, from the Department of Medicine...Show More
Alcohol Withdrawal Syndrome

20:36 | Oct 2nd, 2018

Alcohol withdrawal is a serious problem that can lead to mortality. How to predict if it will occur when a patient who is misusing alcohol is admitted to the hospital is challenging. This Rational Clinical Examination article reports results of a sys...Show More
Treating Appendicitis Without Surgery – 5-Year Follow-up From a Randomized Clinical Trial of Antibiotic Treatment

29:51 | Sep 25th, 2018

In 2015, JAMA published results of a randomized clinical trial showing that antibiotic treatment for acute appendicitis was feasible. Doubters of the efficacy of antibiotics for treating appendicitis were concerned about what the long-term recurrence...Show More
Treating Lyme Disease in 2018, Part 2

29:38 | Sep 18th, 2018

There are new findings about another form of Borrelia: Borrelia miyamotoi. This form of Borrelia causes a relapsing fever but is spread in the same way that Lyme disease is. To help understand these new findings we spoke with Eugene Shapiro, MD, from...Show More
Treating Lyme Disease in 2018, Part 1

24:19 | Sep 11th, 2018

In this JAMA Clinical Reviews podcast, we talk to Eugene D. Shapiro, MD, from Yale University School of Medicine for an update on Lyme disease, including new ideas about its diagnosis and treatment.
What you need to know about syphilis in 2018

30:04 | Sep 4th, 2018

Syphilis is on the rise despite prior successful efforts to control it. Why is it coming back and what needs to be done about it? Dr Charles Hicks from UC San Diego explains. This podcast coincides with updated syphilis screening recommendations from...Show More
Treating Alcohol Use Disorder

23:57 | Aug 28th, 2018

Up to 7% of the entire US population has alcohol use disorder. It’s important for every clinician to understand how to approach patients to question them about their use of alcohol and to establish a diagnosis when alcohol use disorder is present. Dr...Show More
Saving Lives by Stopping Bleeding

21:30 | Aug 14th, 2018

Bleeding is one of the most common preventable causes of death. It is common, yet most people don't know what to do about it when they see it. The Stop the Bleed campaign is an effort to educate the public should they encounter people who are bleedin...Show More
Working on the Precipice: On the Frontlines of the AIDS Epidemic at the CDC, Part II

26:10 | Aug 1st, 2018

As the AIDS crisis unfolded, each discovery seemed to lead to a new mystery. Who was at risk? Why was this disease of immune activation so hard for the body to fight? Most important, what could be done to stop it? In the conclusion of this JAMA Clini...Show More
Working on the Precipice: On the Frontlines of the AIDS Epidemic at the CDC, Part I

24:30 | Jul 24th, 2018

When AIDS first appeared in the gay community in 1981, it was terrifying for patients and clinicians alike. Nobody knew exactly what was going on. But using basic epidemiologic methods, a small team of public servants at the CDC raced against the clo...Show More
Return of the IUD: Long-acting Reversible Contraception Is Safe and Effective

26:20 | Jul 6th, 2018

Misplaced fears about IUDs have caused them to be avoided by many women, despite the fact that they are very safe and among the most effective means for contraception. In this JAMA Clinical Reviews podcast, we review long-acting reversible contracept...Show More
Health Care Spending Gone Wild: Using Expensive Insulin Analogs With Few Clinical Advantages

27:07 | Jun 23rd, 2018

Health care spending in the United States is out of control. The most significant aspect of medical care driving this spending is pharmaceuticals; within pharmaceuticals the greatest increases have been in spending for diabetes medications. The cost ...Show More
A Goal Too Far: Rethinking HbA1c Targets for Diabetes Treatment

29:24 | Jun 19th, 2018

The American College of Physicians just changed its guidance for how aggressively to treat type 2 diabetes, relaxing the HbA1c goal to something below 8 rather than 6.5 or 7 as other organizations recommend. This has stirred up substantial controvers...Show More
When Will It Stop? Clinicians Are Still Ordering Routine ECGs Despite Recommendations to the Contrary

22:12 | Jun 12th, 2018

For many years guidelines have recommended against obtaining ECGs for low-risk patients undergoing routine health examinations. Yet about a fifth of all patients having these exams get an ECG. Why? Are clinicians just stubborn or uninformed or are th...Show More
Replacing the Trachea: An Exciting New Procedure; But How Do We Know It Really Works?

21:55 | May 20th, 2018

Many attempts to replace the trachea have failed in the past. The most spectacular failure was fraudulent research done in Europe by a high-profile surgeon who was eventually charged with scientific misconduct. JAMA now reports a clinical series of s...Show More
Update: New Recommendations for Prostate Cancer Screening

25:41 | May 8th, 2018

The controversy continues about the efficacy of PSA screening for prostate cancer. New recommendations were just issued from the USPSTF about who should be screened for prostate cancer and when. But not everyone agrees with these recommendations. Bal...Show More
Peanut Allergy: The Recommendations Have Changed

19:11 | Mar 6th, 2018

Peanut allergy is common. But it is more common in countries that delay the introduction of peanuts into the diets of infants. Guidelines in the United States previously recommended delayed introduction of peanuts for infants, which resulted in an in...Show More
What Is New in Acute Respiratory Disease Syndrome?

30:19 | Feb 20th, 2018

Acute respiratory disease syndrome is characterized by respiratory failure that occurs after someone is acutely ill, usually from a disease that does not primarily involve the lungs. Its cause, diagnosis, and treatment are reviewed in this JAMA Clini...Show More
Medical Findings In U.S. Government Personnel Reporting Symptoms After Exposure To Sensory Phenomena in Havana, Cuba

29:37 | Feb 14th, 2018

Douglas H. Smith, MD, of the University of Pennsylvania's Department of Neurosurgery and Center for Brain Injury and Repair, and Randel Swanson II, DO, PhD, of the University of Pennsylvania's Physical Medicine and Rehabilitation department, summariz...Show More
The Health of Players of American Football

30:34 | Feb 1st, 2018

The health risks associated with participation in American football have garnered increasing attention over the past several years. Particular focus has been on concussion and the association of repeated head trauma with chronic traumatic encephalopa...Show More
Gastric Sleeve Resection for Obesity: How good Is It?

29:48 | Jan 16th, 2018

Why is two-thirds of the US population overweight or obese? Obesity began to increase in 1980, and its incidence is still rising. One reason for this might be that the population has become tolerant of obesity and accepted it as the normal state. On ...Show More
Surveillance for Thyroid Cancer

16:37 | Jan 2nd, 2018

The incidence of thyroid cancer is increasing. Like so many cancers, it is being diagnosed at earlier stages because of more aggressive screening and diagnostic testing. The aggressiveness of very early stage thyroid cancer is unknown and some of the...Show More
Diagnosis and First-Line Treatment of Chronic Sinusitis

30:23 | Dec 19th, 2017

Sinusitis is one of the most common conditions seen by clinicians. Despite its frequency, it is often misdiagnosed. In this podcast, we review the proper way to establish a diagnosis and treat both acute and chronic sinusitis. Related article
Managing Hypertension: Understanding the New AHA/ACC Hypertension Guideline, Part II

10:37 | Dec 12th, 2017

In November 2017, new guidelines were issued for hypertension treatment. They are a comprehensive overhaul of recommendations for both the diagnosis and treatment of hypertension. Last week, we discussed the guidelines' specific recommendations with ...Show More
Managing Hypertension: Understanding the New AHA/ACC Hypertension Guideline

39:43 | Dec 5th, 2017

In November 2017, new guidelines were issued for hypertension treatment. The new guideline is a comprehensive overhaul of recommendations for both the diagnosis and treatment of hypertension. Based on years of work by dozens of individuals who genera...Show More
Matching Drugs to Genetic Abnormalities to Precisely Treat Cystic Fibrosis

26:07 | Dec 5th, 2017

Cystic fibrosis is a common autosomal recessive disease. It is caused by any one of many discrete genetic abnormalities that affect chloride transport. Identification of specific genetic abnormalities enables clinicians to identify drugs that counter...Show More
Mendelian Randomization: How the Natural Assortment of Genes Can Mimic Randomized Clinical Trials

29:43 | Nov 21st, 2017

The best evidence for proving cause-and-effect comes from randomized clinical trials. However, they are expensive and difficult to perform. The natural assortment of gene variants at birth can mimic randomization in some circumstances and yield impor...Show More
Bacteriophage Treatment for Serious Infections Is Back!

37:28 | Nov 14th, 2017

Bacteriophages are viruses that infect and kill bacteria. When they were first discovered in the early part of the 20th century, there was great enthusiasm for their potential use to treat all sorts of bacterial infections. They were supplanted by an...Show More
Incontinence in Women: How We Talk About It and What Can Be Done

33:42 | Oct 24th, 2017

Urinary incontinence in women is common but not often discussed. Linda Brubaker, MD, and Emily S. Lukacz, MD, review the evaluation and management of incontinence in women, including how to broach the topic with patients and when to use treatments ra...Show More
Managing Transgender Patients: Endocrine Society Guideline Update 2017

25:43 | Oct 17th, 2017

An increasing number of transgender patients are being seen in all care settings. Their medical needs are not too different from those for any primary care patient. New guidelines issued by the Endocrine Society in September 2017 are summarized in th...Show More
Replacing Tissue Biopsies With a Blood Test: The Technique of Liquid Biopsy

26:31 | Oct 3rd, 2017

Powerful new genetic technologies enable clinicians to detect and sequence tiny amounts of free DNA circulating in blood. DNA gets into blood when cells fall apart. Abnormal DNA from diseased cells can be detected, enabling clinicians to detect cance...Show More
Delirium: Prevention, Diagnosis, and Treatment

23:14 | Sep 26th, 2017

Delirium goes unrecognized in approximately 60% of cases. When it is recognized, it can be difficult to treat. Recognizing and treating, as well as preventing, delirium is important because delirium is associated with poor health outcomes and signifi...Show More
Breast Cancer Surgery: Less Is More

34:06 | Sep 12th, 2017

Every successive major clinical trial of less invasive breast cancer surgery seems to show that less is more--less because less surgery seems to not influence outcomes and more because with less surgery, there are fewer complications, resulting in a ...Show More
How Couples With Genetic Disease Can Have Healthy Offspring

15:48 | Sep 5th, 2017

Clinicians can now sample DNA from in vitro blastocysts to identify embryos with genetic abnormalities and avoid implanting them. This genetic screening allows couples who carry dangerous genetic diseases to avoid having children with those diseases....Show More
Are they safe? Drugs and devices receiving accelerated approval by the FDA

27:51 | Aug 15th, 2017

Some drugs and devices receive accelerated approval from the FDA in order to provide potentially important treatments for patients when effective therapies may not be available. These drugs or devices are supposed to have postmarketing studies to def...Show More
How Studying Familial Hypercholesterolemia Resulted in the Discovery of Statins as an Effective Treatment for High Cholesterol

20:53 | Jul 25th, 2017

Scott Grundy, MD, PhD, is a professor of medicine at UT Southwestern in Dallas and is one of a small group of investigators who saved statins from being dumped as a potential drug class. Dr Grundy tells the story of how studying patients with familia...Show More
How to Diagnose and Manage Adult Asthma

33:30 | Jul 18th, 2017

Asthma often develops in childhood but also affects a significant number of adults. It can present in various ways and with varying degrees of severity. William J. Calhoun, MD, of the University of Texas Medical Branch, Galveston, discusses the appro...Show More
Dual Antiplatelet Therapy: Balancing Ischemic and Bleeding Risk

28:43 | Jul 11th, 2017

Following placement of cardiac stents, patients receive dual antiplatelet therapy (DAPT) to prevent stent thrombosis. Prevention of thrombosis is offset by a risk of bleeding. The optimal balance between thrombosis prevention and bleeding risk is not...Show More
Penicillin Allergy – It’s Less Common Than You Think

20:22 | Jul 3rd, 2017

Allergy to penicillin is one of the most commonly reported allergies by patients. In reality, true penicillin allergy is uncommon. Dr. Elizabeth Phillips from Vanderbilt University discusses her experience with testing for penicillin allergy in patie...Show More
High-Intensity Statin Therapy – The Controversy Continues

35:15 | Jun 27th, 2017

Multiple guidelines have been issued regarding how aggressively cholesterol should be managed. These guidelines do not agree with one another and the most significant area of disagreement is in recommendations for high intensity statin therapy. In th...Show More
Diagnosing Congenital and Intellectual Abnormalities With Chromosomal Microarray Analysis

18:27 | Jun 27th, 2017

Chromosomal microarray technology (CMA) facilitates the genetic diagnosis of intellectual disabilities, autism spectrum disorder, and congenital abnormalities in children. Previously, G-band karyotyping was the test performed for this purpose but it ...Show More
Treating Depression in Older Patients

34:45 | May 23rd, 2017

Depression is very common in old age. Because it is associated with many issues related to aging such as having diabetes, hypertension, and other diseases and also the general ability to do less than when a person was younger, it is often assumed tha...Show More
Genomic Sequencing for the Healthy Individual?: Think Smaller

17:14 | May 9th, 2017

Whole-genome sequencing is now easily done for very little cost. It is not known how to interpret the results of this testing. It is inadvisable for healthy individuals to undergo routine whole-genome sequencing but if someone has a reason to suspect...Show More
Diabetes in 2017: Focus Less On HbA1c and More On Cardiovascular Risk Reduction

29:47 | Apr 3rd, 2017

Much has changed recently in diabetes management. The treatment goal has shifted from rigorous glucose control with HbA1c as the primary target to cardiovascular risk reduction. Risk reduction can be achieved in a variety of ways and does not necessa...Show More
JAMA Performance Improvement: Retained Foreign Body From a Sheared Off Lumbar Drain

19:33 | Mar 28th, 2017

A resident is asked to remove a drain that was placed in the lumbar space during an operation. Having never seen this sort of drain before not having removed one, the resident proceeded to remove the catheter. Several days later, the patient complain...Show More
Alzheimer Disease Overview and the Possibility That It’s Caused By Infections

27:37 | Mar 20th, 2017

Alzheimer disease causes progressive neurologic deterioration and is reasonably common in elderly patients. It is characterized by specific patterns of memory loss, which progressively worsens and for which there is no treatment. Recent drug trials h...Show More
Why the New Sepsis Guideline Changed

33:32 | Mar 7th, 2017

Recent guidelines for how to best manage septic shock have changed. Gone are recommendations for central venous oxygen saturation monitoring and goal-directed therapy. In is the concept that septic shock be treated as an emergency with rapid administ...Show More
Updated Guidelines for Sepsis Management

15:36 | Feb 28th, 2017

In 2017 the Society for Critical Care Medicine updated its guidelines for sepsis management. These new guidelines differ significantly from ones in the past in that they no longer recommend protocolized resuscitation and emphasize early and aggressi...Show More
JAMA Professionalism: What Should Students or Residents Do When Abused by Faculty

30:41 | Feb 16th, 2017

Approximately one-third of all medical school graduates report having been abused as students. Medical student and resident abuse has long been considered unacceptable behavior but still persists in the teaching environment. In this podcast we discus...Show More
Sarcopenia, Frailty and Risk Prediction in Geriatric Patients

18:02 | Feb 9th, 2017

As people age, loss of muscle mass is inevitable, resulting in sarcopenia. Muscle loss contributes to overall weakness, which causes frailty. Frailty, in turn, is the generalized susceptibility to disease and injury, all of which causes loss of auton...Show More
Hypertension Management and Dealing With Polypharmacy in Elderly Patients—A Report From the 2016 European Union Geriatric Medical Society Meeting

28:41 | Feb 2nd, 2017

Managing hypertension in elderly patients is complicated. Recent studies have shown that elderly patients may benefit from aggressive hypertension management, but other studies have shown that some are harmed by overly aggressive hypertension managem...Show More
Managing Violent Patients in Health Care Settings

21:55 | Jan 30th, 2017

Workplace violence–related injuries occur disproportionately in health care settings. In this podcast, we discuss how individual clinicians should manage violent patients who might attack them. Article discussed in this episode: Ensuring Staff Safet...Show More
Systematic Approach to a New Onset Seizure

28:14 | Dec 27th, 2016

Between 8% and 10% of the population will have a seizure at one point in life. It's important to distinguish seizures from other entities that can look like them and, once a diagnosis of a seizure is established, know how to treat them. In this podca...Show More
Using Medicare Star Ratings to Select Hospitals

26:54 | Nov 1st, 2016

Medicare recently developed a star rating system to help consumers determine the quality of care delivered at various hospitals. This rating system was considered controversial by many. In this podcast we discuss the rating system with one of its cri...Show More
Treatments for Hyperemesis and Nausea and Vomiting in Pregnancy

18:05 | Oct 4th, 2016

Nearly all women experience some element of nausea and vomiting during their pregnancies. In this podcast we review the entire spectrum of disease all the way up to hyperemesis gravidarum and how to provide care for women experiencing these problems....Show More
Fluid Resuscitation for Patients in Septic Shock

30:40 | Sep 27th, 2016

When managing septic shock, passive leg raising is the best test to determine if a patient is likely to respond to a fluid bolus, better than CVP lines or even bedside ultrasound. Dr Najib Ayas, Associate professor of Critical Care Medicine at the Un...Show More
The High Cost of Pharmaceuticals in the United States

32:46 | Aug 26th, 2016

Drug prices continue to rise in the US. Many solutions have been proposed but few have been implemented. Drs. Janet Woodcock from the FDA and Aaron Kesselheim, author of The High Cost of Prescription Drugs in the United States from the Harvard Medic...Show More
Opioid Use Disorder

34:55 | Aug 11th, 2016

Edward H. Livingston, MD, discusses the British Columbia Ministry of Health’s 2015 guidelines on clinical management of opioid use disorder in adults with Keith Ahamad, MD,  Evan Wood, MD, PhD, ABIM, FRCPC, Tony L. Yaksh, PhD, and Humayun J. Chaudhry...Show More
Treating Opioid Use Disorder Using Buprenorphine Implants

18:41 | Jul 19th, 2016

Richard N. Rosenthal, MD discusses a randomized clinical trial demonstrating the efficacy of an implantable buprenorphine-releasing device for treating opioid use disorder.
Review of Lyme Disease

38:26 | Jul 12th, 2016

Lyme disease is very common in certain regions of the country and is caused by the spirochete Borrelia bergdorferi. Lyme disease is transmitted by tick bites and in this podcast we review the discovery of Lyme disease, its major clinical features, an...Show More
Managing Persistent Diarrhea

37:25 | Jun 28th, 2016

Persistent diarrhea is a poorly recognized syndrome in all populations that requires proper assessment and diagnosis to ensure that affected individuals receive the treatment needed to experience improvement of clinical symptoms. Listen to Drs Herber...Show More
The Discovery of Lyme Disease with Dr Allen Steere

23:03 | Jun 14th, 2016

Dr Allen Steere discovered Lyme disease and discusses what he saw and did when confronted early in his career with a previously undescribed disease. Late stage disease, a form not commonly seen today, is discussed in detail since that is how the dise...Show More
GERD and Esophagitis

29:31 | May 17th, 2016

Drs Stuart Spechler and Peter Kahrilis discuss GERD and esophagitis--how they occur and how they are treated. Dr Spechler also discusses a new hypothesis regarding how reflux esophagitis is caused that differs from the traditional teaching that acid ...Show More
Treating ADHD in Adolescents

25:12 | May 10th, 2016

Attention-Deficit/Hyperactivity Disorder, or ADHD is a very common problem affecting about 10% of all adolescents. Children with ADHD have short attention spans, are hyperactive, talk a great deal, can be disruptive in the classroom etc.-features tha...Show More
Diagnosing Infectious Mononucleosis

33:33 | Apr 12th, 2016

Mononucleosis is a common disease of young adults manifested by lethargy, fever, pharyngitis, lymphadenopathy and splenomegaly. In this podcast, we review the clinical features of the disease and how good each of them is at establishing a diagnosis o...Show More
Opioid Prescribing: Rising to the Challenge

23:00 | Mar 15th, 2016

An opioid abuse epidemic now plagues US healthcare. It was caused, in part, by overzealous advocacy for controlling chronic pain resulting in overuse of narcotics. There are now 2 million Americans addicted to opioids. The approach for treating chron...Show More
Treating Geriatric Polypharmacy by Deintensifying Unnecessary Diabetes Treatment

27:28 | Mar 8th, 2016

Polypharmacy is a rapidly worsening problem that hits elderly patients particularly hard.  As patients grow older, they need more medications but at the same time become less capable of managing the complexity of drug treatments.  In order to simplif...Show More
2015 Breast Cancer Screening Recommendations for Women at Average Risk

22:39 | Feb 23rd, 2016

The American Cancer Society breast cancer screening guidelines have been changed to recommend annual screening for women older than 45 and every other year screening for women older than 55. Older women should only pursue screening if they have a mor...Show More
Antibiotic Therapy for Community-Acquired Pneumonia in Adults

18:42 | Feb 9th, 2016

Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not cl...Show More
New Dietary Guidelines

25:19 | Feb 2nd, 2016

The 2015-2020 US Dietary Guidelines for Americans were recently released. They are intended to provide guidance for health policy officials and clinicians regarding healthy diets and establishing goals for improving nutrition. These are important sin...Show More
Peripheral Neuropathy

26:43 | Jan 19th, 2016

Peripheral neuropathy is a highly prevalent and morbid condition affecting 2% to 7% of the population. Patients frequently experience pain and are at risk of falls, ulcerations, and amputations. It is most commonly occurs in patients with diabetes. F...Show More
Advances in Diagnosis and Treatment of Constipation

27:57 | Jan 12th, 2016

Constipation is one of the most frequent problems clinicians are asked to deal with. Despite how common it is, constipation is frequently not treated adequately. In this podcast, Arnold Wald, MD, explains a stepwise approach to the management of cons...Show More
Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

19:21 | Dec 29th, 2015

Appendicitis is one of the most common reasons people undergo abdominal surgery. Lost in history are the reasons why appendectomy was performed in the first place, and in the hundred years since appendicitis was first described, many changes in patie...Show More
Head Trauma

25:35 | Dec 22nd, 2015

Minor head trauma usually does not cause significant brain injury. To be safe, clinicians often obtain head CT scans to ensure no major injury is present. For minor head trauma (Glascow coma scale 13-15), the risk to benefit ratio for head CT is usua...Show More
Graves Disease

24:49 | Dec 15th, 2015

Edward H. Livingston, MD discusses Graves disease with David Cooper, MD, author of Management of Graves Disease: A Review
Prostate Cancer Screening

18:52 | Nov 17th, 2015

Edward H. Livingston MD, explores the topic of prostate cancer screening in author interviews with: Dan Merenstein about losing a malpractice case despite following evidence-based medicine guidelines (PSA Screening — I Finally Won!). Otis Brawley ab...Show More
Ruling Out Acute Coronary Syndrome in Patients With Chest Pain

17:30 | Nov 8th, 2015

ACS is a common and potentially lethal problem. However, only about 10% of patients who present to an emergency department with chest pain actually have ACS. In this JAMA Clinical Reviews podcast, we discuss which signs, symptoms and tests used to ma...Show More
Using Likelihood Ratios to Understand How Chest Pain Predicts Acute Coronary Syndrome

14:58 | Nov 8th, 2015

Interview with David Simel, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review
Explaining the Improved Health of the US: Mortality Trends 1969-2013

19:02 | Oct 27th, 2015

Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013, and J. Michael McGinnis, MD, MPP, author of Mortality Trends and Signs of Health Progress. Also in this episode is a conversation with C...Show More
Treating Chronic Sinusitis in Adults

24:55 | Sep 1st, 2015

Interview with Luke Rudmik, MD, MSc, author of Medical Therapies for Adult Chronic Sinusitis: A Systematic Review. This systematic review summarizes the evidence-based medical treatment of adult chronic sinusitis and proposes a treatment algorithm.
Posttraumatic Stress Disorder

23:11 | Aug 4th, 2015

Edward H. Livingston, MD, interviews a war veteran and discusses PTSD with Maria Steenkamp, PhD, author of Psychotherapy for Military-Related PTSD, and Michele Spoont, PhD, author of Rational Clinical Exam: Does This Patient Have Posttraumatic Stress...Show More
Managing Atrial Fibrillation

22:30 | Jul 21st, 2015

Edward H. Livingston, MD discusses atrial fibrillation with Eric N. Prystowsky, MD, author of Treatment of Atrial Fibrillation, and talks about new technologies to facilitate screening for atrial fibrillation with Leslie Saxon, MD.
Medical Marijuana for Treatment of Chronic Pain and Other Problems

19:25 | Jun 23rd, 2015

Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Ho...Show More
Stroke Prevention in Atrial Fibrillation

18:41 | May 19th, 2015

Edward H. Livingston, MD discusses stroke prevention in atrial fibrillation with Gregory Lip, MD, author of Stroke Prevention in Atrial Fibrillation: A Systematic Review

19:26 | May 12th, 2015

Read the article and earn CME: bit.ly/1T3EpB1 Patient Page: bit.ly/1T3Exk0 Spanish Patient Page (Acalasia):  bit.ly/1T3EHrr   Understanding the swallowing disorders dysphagia and achalasia as explained by John Pandolfino, MD from Northwestern Univers...Show More