The Cyclo Edition Podcast
1) Asymmetric Hydroamination
In this episode we discuss a report from the Hartwig lab on an enantioselective hydroamination reaction. Through rational catalyst design, a cationic iridium complex was discovered that adds an amine ...Show More
2) Mark Levin Interview
In this episode we interview Mark Levin, an Assistant Professor at UChicago. We discuss his recent publication with the Jacobsen group, life as a new professor, and places to eat in Chicago.
3) Difluorinated Alkyl Bromide Synthesis via Chiral Iodoarene Catalysis
In this episode we discuss a report from the Jacobsen lab on an enantioselective synthesis of difluorinated alkyl bromides catalyzed by a chiral iodoarene. Linear free energy relationships between exp...Show More
4) Marshall Brennan Interview
In this episode we interview Marshall Brennan, the founder and Senior Product Manager of ChemRxiv. We discuss open-access publishing, alternative chemistry careers, and much more.
5) Daniele Leonori Interview
In this episode we interview Dr. Daniele Leonori, who is a professor of chemistry at the University of Manchester. We discuss his recent paper on dehydrogenative aniline synthesis, differences between...Show More
6) Dehydrogenative Aniline Synthesis
In this episode we discuss a report from the Leonori lab on a photochemical dehydrogenative strategy for aniline synthesis. Photoredox and cobalt catalysis are combined to transform cyclohexanones int...Show More
7) M. Christina White Interview
In this episode we interview Dr. M. Christina White, who is a professor of chemistry at the University of Illinois. We discuss her recent paper on C–H methylation as well as her program on site-select...Show More
8) Late-Stage C–H Methylation
In this episode we discuss a report from the White lab on a new method for late-stage C–H methylation adjacent to heteroatoms. DOI: 10.1038/s41586-020-2137-8
9) Total Synthesis of Maximiscin
In this episode we discuss the total synthesis of (–)-maximiscin reported by the Baran lab. The route takes advantage of a convergent fragment coupling strategy with a late-stage formation of the cent...Show More
10) Photocatalytic Deracemization
In this episode we discuss a report from the Knowles lab on a method for catalytic deracemization using visible light. This strategy benefits from two independent stereoselective steps resulting in a ...Show More