Unraveled Podcast
1) Season 2 Episode 6: Big Data, AI, and Cancer Research
As our universe of knowledge expands, sometimes incrementally and more often, exponentially, its new dimensions create new challenges. The more we know, the better our tools are, the more choices we h...Show More
2) Season 2 Episode 5: With a Little Help From My Friends: Combination Immunotherapy
If there is such a thing as a holy grail in cancer research, a secret spell or golden ring that can ward off any and all forms of the disease, it probably lives somewhere in the realm of immunotherapy...Show More
Season 2 Episode 5: With a Little Help From My Friends: Combination Immunotherapy
32:21 | Apr 26th, 2023
3) Season 2 Episode 4: Making it Personal: Targeted Cancer Therapies
By the early 2000s, researchers at Dana-Farber and elsewhere knew that a certain protein appeared in many tumors taken from lung cancer patients. Based on that data, doctors started treating those pat...Show More
4) Season 2 Episode 3: Stop the Division: CDK-4/6 Inhibitors and the Cell Cycle
Cancer is often a problem of cell division; cancer cells keep doubling and doubling, faster and faster. Eventually, they crowd out the healthy cells we need to survive. So researchers proposed a quest...Show More
Season 2 Episode 3: Stop the Division: CDK-4/6 Inhibitors and the Cell Cycle
26:59 | Mar 15th, 2023
5) Season 2 Episode 2: Thalidomide and its Second Act in Multiple Myeloma
Momentum isn't always one way. And it's not always constant. Sometimes it shoves you sideways, sometimes it stops you in your tracks. And sometimes only sometimes, it drives you to write one of the mo...Show More
6) Season 2 Episode 1 BCL-2 Inhibitors: Driving Cells to Destruction
The story begins decades ago with a man named Stanley Korsmeyer, who led the molecular oncology program at Dana-Farber from 1998 until his death in 2005. He discovered that B-cell cancers like CLL ove...Show More
7) Season 2 Trailer
In season 2 of Unraveled, we explore the theme of momentum. The momentum that takes therapies from test bench to bedside, and then back to test bench for fine tuning. The momentum provided by research...Show More
8) Episode 6: Dana-Farber in the Time of COVID
A beauty… that in some cases becomes tragic. It’s not the way most people would describe a virus. In the simplest of terms, a virus is a snippet of genetic code. It can’t reproduce on its own. So, in ...Show More
9) Episode 5: Turning Science Fiction into Fact
It’s always fun to think about the future. Flying cars. Cities in the clouds. Colonies on Venus and Mars. Ok. So we didn’t end up living like the Jetsons. But a few of those visions did come true. And...Show More
10) Episode 4: The Blueprints of Your Cells
There are approximately 20,000 genes in the human genome. 20,000 packets that house the blueprints for every human cell. And every human cell contains a complete copy of that genome. It’s an incredibl...Show More